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CDMO

Our strong Synthetic, Organic Chemistry and Manufacturing Capabilities, makes us a one-stop-shop for Custom Development and Manufacturing (CDMO) services and emerge as ‘Partner of Choice’ to global Pharmaceutical and Agrochemical customers.

We have a strong relationship with 19 out of 25 Global Innovator Pharmaceutical companies and 7 of top 10 Global Agrochemical companies. We are continually collaborating on late-phase and launch products with Pharma innovators and Biotech companies. We have also worked on key intermediates for Remdesivir, the first US FDA-approved Antiviral drug for Covid-19.

Our contract manufacturing portfolio includes customised solutions for the pharmaceutical and agrochemical industry for both cGMP and non-cGMP products.

Our solutions include route design, process development, process optimisation, scale-up and commercial manufacturing of intermediates starting from a few Kgs to Multi Metric Tons of specific products as desired by customers.

We operate through 5 world-class manufacturing sites having 13 Multi-Product Plants strictly adhering to cGMP Guidelines. Some of our strategic operations are centered at external manufacturing sites also. Most of our sites are audited by Pharma & Agro customers. Our commercial plants are equipped to handle multi-chemistry and can operate at a wide range of process conditions (-80 C to 550 C and absolute vacuum).

We have over 120 reactors (MSGL, SS, Hastelloy & Cryogenic) capable of handling 1 KL-16 KL with a total reactor volume of over 600 KL including fixed bed and fluidized bed catalytic reactors.

Our robust pilot plant capabilities include a cGMP compliant facility with 30 reactors ranging from 20-1000 L (Glass assemblies, Cryogenic Rectors, Plug Flow reactors and autoclaves. They operate at a temperature of -80 °C to 280 °C and can handle pressure upto 58 kg/cm2

We have expertise in handling 35 key technology platforms. We are specialized in Handling Grignard Reactions, Photochlorination, Bulk Chlorination and Fluorination with HF & KF at our dedicated photochlorination & fluorination facilities. Our hands-on experience on Complex Multi-Step Synthesis, Chiral Synthesis, Cyanation & Oleum processes, Fractionation by sophisticated and highly efficient structured packing-based distillation columns gives us an unmatched edge over our competitors. We added new chemistry technologies like Sugar Chemistry & Pinner Reaction in our existing Technology Platform.

We believe in providing our customers a renewable supply chain and hence all the ingredients in our portfolio are based on renewable materials. Committed to sustainable operations, we are Responsible Care® 14001:2003 certified under the American Chemistry Council’s (ACC) Responsible Care® program for our Corporate Office, Noida and for the Manufacturing Unit Gajraula. Our facilities are ISO 18000 certified and we are also EcoVadis gold rated and our performance is among top 5% CSR companies globally.

We are committed to adhering to strict Quality & Regulatory Compliance and our dedicated regulatory team ensures that all our in-house technologies comply with global regulatory guidelines. Our Quality Management Systems are in line with ISO 9001.

A dedicated team of experienced professionals including engineers, R&D scientists, quality assurance specialists and project management experts are committed to following a customer-centric approach to deliver value and understand all shades of customization.

Our Capabilities

Key Chemistry & Technologies

  • Specialized in Handling Grignard Rxn annualy at 100’s of MT annually & Photochlorination at 1000’s of MT annually Bulk chlorination facility at 1000’s of MT annually
  • Dedicated Fluorination facility with HF & KF.
  • Hands on Experience on Chiral Synthesis, Cyanation & Oleum processes.
  • Fixed bed and Fluidized Bed Catalytic reactors
  • Distillation using highly efficient distillation Columns of 110-120 theoretical Stages.
  • Handling Lachrymatic reactions at high volumes.

Core Technologies

  • Alkali Metal Cyanide
  • Alkylation (Methylation)
  • Amination
  • Amoxidation
  • Aromatisation
  • Balz-Schiemann
  • Beckmann Rearrangement
  • Bio-transformations
  • Bromination
  • Butyl Lithium Reaction (upto 80°C)
  • Chichibabin Reaction
  • Chlorination
  • Claisen Condensation
  • Cyclocondensation
  • Dealkylation
  • Dehydration
  • Diazotisation
  • Ethoxylation
  • Fermentation
  • Fluorination using KF & HF
  • Grignard Reaction
  • Halogenation & Dehalogenation
  • Hanzch Synthesis
  • Hoffman Rearrangement
  • Hydrogenation(Including high pressure)
  • Mannich Reaction
  • Methoxylation
  • Nitration
  • Oxidation
  • Phosphate Esters/POCl3 Handling
  • PolyState studies
  • Process intensification
  • Quaternization
  • Reduction ( High Pressure Hydrogenation)
  • Sandmeyer Reaction
  • Sodamide/Sodium methoxide Reaction
  • Stereo Selective Hydrogenation/Oxidation
  • Transesterfication
  • Vapour Phase Reaction (upto 450°C)

Pilot plant

  • GMP Compliant Pilot Plant facility with reactors ranging from 20 L to 630 L (Including Glass assemblies and cryogenic reactors, autoclaves)
  • Reactors with a combination of GLR/ SS / Hastelloy with further expansion of liquid and solid effluent .
  • Operating temperature range of -90°C to 240°C , Autoclaves (upto 58 kg/cm2).

Commercial Capabilities

  • Commercial Plants have over 100 reactors (Mild Steel Glass Lined reactors (MSGL), Stainless Steel (SS) 304, 316, hastelloy & Cryogenic)
  • Size ranging from 1 KL to 14 KL with total reactor volume of about 600 KL
  • Wide range of process conditions ( temp -80°C to 240°C, absolute Vacuum) for multi-product manufacturing
  • Flexible scalability to suit custom products with wide range of combinations for retro-fitments available.

GMP capabilities

  • GMP facility at Bharuch SEZ for Advanced Intermediates and API to meet your regulated market requirements.
  • Temperature, humidity and differential pressure controlled (Building management system) areas & ISO-8 (Class 1,00,000) clean rooms to avoid Cross contamination.
  • The facility has around 5-6 KL volume reactors with Combination of MSGL & SS-316 suiting your product needs.
  • GMP facility with single-pass air controls to prevent contamination.
  • Dedicated HVAC systems for each suite,Powder processing area with quarantine, FG reject material storage, FG storage with pass box.

Utilities

  • Captive Power Generation facility with spare capacities.
  • Self Sustained Steam generating unit , Chilled Water & Brine unit with spare capacities.

Waste Management Overview

  • Zero liquid discharge plant
  • Multi Effect Evaporators
  • Liquid Incinerators & Spray Dryers
  • Bio-composting, secure landfills and landfill sites
  • Thermal Oxidizers
  • Incineration facility for liquid and gaseous wastes with online vent gas monitoring

Committed to the Responsible Care® initiative

Responsible Care® is a voluntary commitment by the global chemical industry to drive continuous improvement and achieve excellence in environmental, health and safety and security performance.

At Jubilant, we value the health, safety and security of our employees, customers, suppliers, neighbours and the environment. As we work towards a sustainable future we ensure that our products are handled safely, Responsible Care principles are supported across the business value chain. We believe that being sustainable is an everyday practice and not just an idea and that’s why we work towards continuous improvement and share our progress with customers, employees and local communities.

At Jubilant, every employee has an important role in fulfilling our commitment to Responsible Care and continually improving our performance.

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Life Science Ingredients (LSI) business of Jubilant Life Sciences Awarded Permission to use Responsible Care Logo

The LSI business has been awarded permission to use Responsible Care logo by the Indian Chemical Council. The development is a result of successful audits across the Corporate Office and Manufacturing Facilities based on the 6 codes of Management Practicescertified

  • Product Stewardship
  • Process Safety
  • Distribution
  • Pollution Prevention
  • Employee Health & Safety
  • Emergency Response & Community Awareness

Jubilant Life Sciences is a committed member of the Responsible Care program and demonstrates a continuing commitment to environmentally responsible business practices.

Life Science Ingredients business of Jubilant Life Sciences now Responsible Care® 14001:2015 certified

Continuing our commitment to deliver value through safe and sustainable practices, Life Science Ingredients business of Jubilant Life Sciences (JLL) has received Responsible Care®14001:2015 certification under the American Chemistry Council’s (ACC) Responsible Care® program for its Corporate Office in Noida and Gajraula Manufacturing Unit. JLL is one of the few companies in India to receive this certification demonstrating our robust management systems which ensures high standards of health, safety, security and environmental performance for both its products and operations.

About Responsible Care®

Responsible Care® is the global chemical industry’s environmental, health and safety (EHS) initiative to drive continuous improvement in performance. Through this initiative the Companies achieve the objective of going beyond legislative and regulatory compliance. Responsible Care was launched in 1985 by the Canadian Chemical Producers’ Association and is now implemented globally through national and regional associations such as the American Chemistry Council and others. It was adopted by American Chemistry Council (ACC) in 1988. Responsible Care is both an ethic and a commitment that seeks to build confidence and trust in an industry that is essential to improving living standards and the quality of life. Current Elements include:-

  • RC 14001:2015 Certification
  • Responsible Care Guidelines
  • Responsible Care Global Charter

Our Guiding Principles

There are some guiding principles of Responsible Care which are initiatives to improve our environment, health, safety and security performance.

  • Lead our company in ethical ways that increasingly benefits society, the economy and the environment.
  • Design and develop products that can be manufactured, transported, used and disposed of or recycled safely.
  • Work with customers, carriers, suppliers, distributors and contractors to foster the safe and secure use, transport and disposal of chemicals and provide hazard and risk information that can be accessed and applied in their operations and products.
  •  To design and operate our facilities in a safe, secure and environmentally sound manner.
  • To instill a culture throughout all levels of our organizations to continually identify, reduce and manage process safety risks.
  • To promote pollution prevention, minimization of waste and conservation of energy and other critical resources at every stage of the life cycle of our products.
  • To cooperate with governments at all levels and organizations in the development of effective and efficient safety, health, environmental and security laws, regulations and standards.
  • To support education and research on the health, safety, environmental effects and security of our products and processes.
  • To communicate product, service and process risks to our stakeholders and listen to and consider their perspectives.

Dedicated Project Management Team Overview

  • Dedicated certified Project Managers for individual projects for your tailored requirements & needs.
  • Communicates periodically with customers on project progression, documentation, etc. in a mutually agreed reporting format
  • Identify risks and their mitigation plans to ensure timely implementation of projects.
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